abstract：OBJECTIVE:To determine the impact of a broad spectrum of different polymorphisms within the interleukin-10 (IL-10) promoter gene on disease susceptibility to primary Sjogren's syndrome (pSS), clinical manifestations, and autoantibody production. METHODS:We genotyped 111 unrelated German Caucasian patients with pSS and...

journal_title：Scandinavian journal of rheumatology

authors： Willeke P,Gaubitz M,Schotte H,Becker H,Domschke W,Schlüter B

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:To determine the serum concentration of tumour necrosis factor (TNF)-related weak inducer of apoptosis (TWEAK) in patients with rheumatoid arthritis (RA) and to investigate the relationship between TWEAK level and disease activity, proinflammatory cytokine levels, and response to anti-TNF treatment. METHODS...

journal_title：Scandinavian journal of rheumatology

authors： Park MC,Chung SJ,Park YB,Lee SK

更新日期：2008-05-01 00:00:00

abstract：:Vibrio vulnificus infection commonly presents as sepsis or wound infection. A case of alcoholic liver cirrhosis developed acute left heel pain and swelling 2 days after ingesting raw fish. Two sets of blood cultures indicated V. vulnificus. HLA-B27 was negative. Ultrasonography revealed left Achilles tendinitis. Fluid...

journal_title：Scandinavian journal of rheumatology

authors： Yang CH,Shie SS,Yu KH,Jan Wu YJ

更新日期：2008-05-01 00:00:00

abstract：:Primary Sjögren's syndrome (pSS) is a connective tissue disease with symptoms and serological findings often overlapping with systemic lupus erythematosus (SLE) (1). Thromboembolic events are common in SLE but not in pSS (2)(3). However, case reports have described pSS patients who developed fulminant multiorgan disea...

journal_title：Scandinavian journal of rheumatology

authors： Haga HJ,Jacobsen EM,Peen E

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:The main aim of the study was to examine whether patients with spondyloarthritides underwent their first coronary artery bypass grafting (CABG) at a younger age than those without spondyloarthritides. METHODS:Patients who underwent their first CABG at the Feiring Heart Clinic during 2001-2005 were preoperat...

journal_title：Scandinavian journal of rheumatology

authors： Hollan I,Saatvedt K,Almdahl SM,Mikkelsen K,Moer R,Halvorsen P,Veel T,Førre OT

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of adalimumab, etanercept, and infliximab in patients with established rheumatoid arthritis (RA) taking concomitant methotrexate (MTX) by calculating the number needed to treat (NNT) using three different methods. METHODS:A systematic literature search of the Cochrane Library, MEDLINE...

journal_title：Scandinavian journal of rheumatology

authors： Kristensen LE,Christensen R,Bliddal H,Geborek P,Danneskiold-Samsøe B,Saxne T

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The results of previous studies on the association between bone mineral density (BMD) and chronic spinal syndromes have been contradictory. Therefore, we studied relative BMD measured by the metacarpal index (MCI) and its associations with chronic neck and low-back syndromes and diffuse idiopathic skeletal h...

journal_title：Scandinavian journal of rheumatology

authors： Haara MM,Arokoski JP,Kröger H,Kärkkäinen A,Manninen P,Knekt P,Impivaara O,Heliövaara M

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Interleukin-1 (IL-1) has been implicated in the pathogenesis of several rheumatic inflammatory diseases, including adult-onset Still's disease (AOSD) and systemic-onset juvenile idiopathic arthritis (SoJIA). Several clinical trials also suggest that anakinra, a human recombinant interleukin-1 receptor antagon...

journal_title：Scandinavian journal of rheumatology

authors： Youm JY,Woo JH,Kim TH,Bae SC,Yoo DH

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:Platelets are thought to participate in the pathogenesis of chronic inflammatory diseases such as rheumatoid arthritis (RA). We showed recently an in vivo increase in platelet-endothelial cell interactions in mice with antigen-induced arthritis (AiA). The underlying mechanisms are not yet clear. The aim of th...

journal_title：Scandinavian journal of rheumatology

authors： Schmitt-Sody M,Metz P,Klose A,Gottschalk O,Zysk S,Hausdorf J,Veihelmann A,Jansson V

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:We sought to investigate the cost of living with rheumatoid arthritis (RA) and evaluate the influence of both demographics and specific disease characteristics on these costs. METHODS:We used a population-based questionnaire to survey 895 patients living in the city of Malmö, Sweden, during 2002. Data were o...

journal_title：Scandinavian journal of rheumatology

authors： Jacobsson LT,Lindroth Y,Marsal L,Juran E,Bergström U,Kobelt G

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To analyse the levels of interleukin-6 (IL-6) in the synovial fluids and sera of patients with osteoarthritis (OA) and to identify the IL-6-secreting cells. METHODS:Serum, synovial fluid, synovial tissue, and articular cartilage samples were collected from 49 OA patients with end-stage knee or hip OA who und...

journal_title：Scandinavian journal of rheumatology

authors： Doss F,Menard J,Hauschild M,Kreutzer HJ,Mittlmeier T,Müller-Steinhardt M,Müller B

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of spondyloarthropathies (SpA) in an adult population in Marche, a region located in central Italy. METHODS:A cross-sectional population-based study was conducted on a target adult population of 20 882. Questionnaires were sent to a random sample of 3664 individuals aged 18 years a...

journal_title：Scandinavian journal of rheumatology

authors： De Angelis R,Salaffi F,Grassi W

更新日期：2007-01-01 00:00:00

abstract：:Cogan's syndrome (CS) is a rare multisystemic disease characterized by vestibuloauditory dysfunction, inflammatory eye disease and vasculitis. Aortic aneurysms due to aortitis are under-recognized in CS, and are potentially fatal, with two of eight reported cases dying from aneurysm/arterial rupture. The presence of a...

journal_title：Scandinavian journal of rheumatology

authors： Low AH,Su JW,Sin KY,Fong KY,Thumboo J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To investigate the influence of -308 tumour necrosis factor-alpha (TNFalpha) promoter polymorphism and circulating TNFalpha levels in the clinical response to adalimumab treatment in patients with rheumatoid arthritis (RA). METHODS:Eighty-one patients with active RA were genotyped for the -308 TNFalpha polym...

journal_title：Scandinavian journal of rheumatology

authors： Cuchacovich M,Soto L,Edwardes M,Gutierrez M,Llanos C,Pacheco D,Sabugo F,Alamo M,Fuentealba C,Villanueva L,Gatica H,Schiattino I,Salazaro L,Catalan D,Valenzuela O,Salazar-Onfray F,Aguillón JC

更新日期：2006-11-01 00:00:00

abstract：:We report the case of a 41-year-old man diagnosed with Still's disease. Multiple disease-modifying anti-rheumatic drug (DMARD) therapies failed to induce disease remission or to prevent progressive joint destruction. The man presented with active arthritis and classical Still's rash accompanied by fever. Anti-tumour n...

journal_title：Scandinavian journal of rheumatology

authors： Thonhofer R,Soleiman A,Kriessmayr M,Thonhofer U,Wipfler E,Gaugg M,Eder S,Erlacher L

更新日期：2006-11-01 00:00:00

abstract：:Dorland's Illustrated Medical Dictionary gives the following definition of dactylitis (deltaalphachitauupsilonlambdaomicronsigma = digit): 'inflammation of a finger or toe'. Although any inflammatory process involving the fingers or toes may be called dactylitis, the term has entered in current use only in some well-d...

journal_title：Scandinavian journal of rheumatology

authors： Olivieri I,Scarano E,Padula A,Giasi V,Priolo F

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of interstitial lung disease (ILD) in patients with different forms of connective tissue disease (CTD) using non-invasive procedures including high-resolution computed tomography (HRCT) and to evaluate the relationship between the imaging and functional status of the patients. METHO...

journal_title：Scandinavian journal of rheumatology

authors： Afeltra A,Zennaro D,Garzia P,Gigante A,Vadacca M,Ruggiero A,Dardes N,Navajas MF,Zobel BB,Amoroso A

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To study mortality from infections and accuracy of pre-mortem diagnoses in patients with rheumatoid arthritis (RA) autopsied during a 40-year period. METHODS:We investigated infectious causes of death, findings at autopsy, and clinicians' estimation of cause of death in 369 consecutively autopsied RA and 371...

journal_title：Scandinavian journal of rheumatology

authors： Koivuniemi R,Leirisalo-Repo M,Suomalainen R,Piirainen H,Paimela L

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:To compare the prognosis of subacromial impingement (SAI) stage II treated conservatively or with subacromial decompression. METHODS:A follow-up study after 4-8 years in a randomized controlled trial (RCT) with 90 adult cases with SAI treated in a Danish hospital from 1996 to 2000 with graded physiotherapy ...

journal_title：Scandinavian journal of rheumatology

authors： Haahr JP,Andersen JH

更新日期：2006-05-01 00:00:00

abstract：:With improved disease survival, arterial thromboembolism has become an important cause of morbidity in patients with systemic lupus erythematosus (SLE). A number of conventional and non-conventional risk factors are associated with accelerated atherosclerosis. Regular surveillance and control of traditional risk facto...

journal_title：Scandinavian journal of rheumatology

authors： Mok CC

更新日期：2006-03-01 00:00:00

abstract：:We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infections were discoun...

journal_title：Scandinavian journal of rheumatology

authors： Llanos C,Soto L,Sabugo F,Gallegos I,Valenzuela O,Verdaguer J,Cuchacovich M

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:To determine whether HLA-DR alleles are associated with the development and clinical features of systemic sclerosis (SSc) in Koreans. METHODS:Seventy-nine patients (74 women and five men; 45 diffuse types and 34 limited types; mean age at diagnosis 43.9 years) fulfilling the American College of Rheumatology ...

journal_title：Scandinavian journal of rheumatology

authors： Joung CI,Jun JB,Chung WT,Song GG,Choe JY,Chang HK,Yoo DH

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Aseptic loosening is one of the most important problems that can occur after total hip arthroplasty (THA). In this study, we analysed levels of large tenascin-C (TN-C) variants and compared them in pseudosynovial fluid from patients with aseptic loosening after THA with those in synovial fluid from patients u...

journal_title：Scandinavian journal of rheumatology

authors： Hasegawa M,Sudo A,Nagakura T,Hirata H,Kinoshita N,Yoshida T,Uchida A

更新日期：2005-11-01 00:00:00

abstract：:Assessment of health-related quality of life (HRQoL) is relevant for the patients and is important in both clinical research and daily clinical practice. Generic and disease-specific instruments for assessment of HRQoL are reviewed. Changes in HRQoL provide important information on randomized controlled clinical trial...

journal_title：Scandinavian journal of rheumatology

authors： Kvien TK,Uhlig T

更新日期：2005-09-01 00:00:00

abstract：:Adult Still's disease (ASD) is a rare systemic disorder characterized by fever, arthralgia, cutaneous rash, and lymphadenopathy, with high polymorphonuclear leucocytosis and low glycosylated ferritinaemia. Kidney involvement has been reported rarely. We present a patient with ASD who developed haemolytic uraemic syndr...

journal_title：Scandinavian journal of rheumatology

authors： Quéméneur T,Noel LH,Kyndt X,Droz D,Fleury D,Binaut R,Lemaitre V,Gobert P,Vanhille P

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:To (i) examine the association between fatigue, psychosocial work characteristics (job control, support, participation in decision making, psychological job demands), and physical work requirements on the one hand and work ability of employees with rheumatoid arthritis (RA) on the other, and (ii) determine t...

journal_title：Scandinavian journal of rheumatology

authors： de Croon EM,Sluiter JK,Nijssen TF,Kammeijer M,Dijkmans BA,Lankhorst GJ,Frings-Dresen MH

更新日期：2005-07-01 00:00:00

abstract：:Rituximab is a genetically engineered chimeric monoclonal immunoglobulin (Ig)G1 antibody. It binds the CD20 trans-membrane surface antigen expressed by mature B cells but not by antibody secreting plasma cells, and removes the cells by activating complement, inducing cell-mediated lysis, and by apoptosis. Mainly used ...

journal_title：Scandinavian journal of rheumatology

authors： Omdal R,Wildhagen K,Hansen T,Gunnarsson R,Kristoffersen G

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of low-dose oral methotrexate (MTX) as treatment for patients with Kawasaki disease (KD) resistant to intravenous immunoglobulin (IVIG). METHODS:The subjects were four patients with KD, aged 8 months to 8 years old, who showed persistent disease after treatment with high-dose IVIG (2 g...

journal_title：Scandinavian journal of rheumatology

authors： Ahn SY,Kim DS

更新日期：2005-03-01 00:00:00

abstract：:Glucocorticoids (GCs) have powerful and potent anti-inflammatory and immunomodulatory effects in rheumatoid arthritis (RA) and many other diseases. These effects are mediated by up to four different mechanisms of action: cytosolic glucocorticoid receptor (cGCR)-mediated classical genomic and rapid non-genomic effects,...

journal_title：Scandinavian journal of rheumatology

authors： Buttgereit F,Saag KG,Cutolo M,da Silva JA,Bijlsma JW

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To determine the expression of bcl-2, p53, and caspase 3, and measure the Ki-67 proliferation index as well as DNA content and DNA fragmentation in a case of diffuse pigmented villonodular synovitis (PVNS) of the knee with aggressive clinical behaviour. METHODS:Expression of p53, Bcl-2 and Ki-67 was investig...

journal_title：Scandinavian journal of rheumatology

authors： Berger I,Paessler HH,Weckauf H,Ehemann V,Helmchen B

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To measure serum levels of antibodies against cyclic citrullinated peptide (anti-CCP antibodies) and serum cartilage oligomeric matrix protein (COMP) in patients with early joint inflammation, and to study the correlation of these two tests with clinical measurements. METHODS:Adult patients with recent-onset...

journal_title：Scandinavian journal of rheumatology

authors： Söderlin MK,Kastbom A,Kautiainen H,Leirisalo-Repo M,Strandberg G,Skogh T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The diagnosis of Achilles and patella tendinitis has until recently been based on clinical examination, and treatment with local steroid injection has been given blindly. This is the first randomized, double blind, placebo-controlled study of local steroid injection in athletes with chronic tendinitis, which...

journal_title：Scandinavian journal of rheumatology

authors： Fredberg U,Bolvig L,Pfeiffer-Jensen M,Clemmensen D,Jakobsen BW,Stengaard-Pedersen K

更新日期：2004-01-01 00:00:00

abstract：:This study sets out to determine predictors of marital and sexual satisfaction in patients with rheumatoid arthritis (RA) and their spouses. Fifty-nine patients and their spouses completed questionnaires independent from each other. Multiple correlations with marital and sexual satisfaction were computed for demograph...

journal_title：Scandinavian journal of rheumatology

authors： van Lankveld W,Ruiterkamp G,Näring G,de Rooij DJ

更新日期：2004-01-01 00:00:00

abstract：:Using Doppler echocardiography (DE), we measured pulmonary arterial systolic pressure (PASP) in rheumatoid arthritis (RA) patients without coexisting cardiopulmonary diseases. Accepting the normal upper limit of PASP as 30 mmHg, we found elevated PASP in 11 out of 40 (27.5%) RA patients, values being mostly 30-40 mmHg...

journal_title：Scandinavian journal of rheumatology

authors： Keser G,Capar I,Aksu K,Inal V,Danaoğlu Z,Savas R,Oksel F,Tunc E,Kabasakal Y,Kitapcioglu G,Doganavsargil E

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To analyse the relative role of HLA-DR antigens in the susceptibility to, and clinical expression of psoriatic arthritis (PsA). PATIENTS AND METHODS:A retrospective cohort study of 120 patients with PsA who were assessed according to a standard protocol. Patients were classified in accordance with the predom...

journal_title：Scandinavian journal of rheumatology

authors： Queiro-Silva R,Torre-Alonso JC,Tinturé-Eguren T,López-Lagunas I

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:This study examined differences in reactions to disability between early and established rheumatoid arthritis (RA) patients, and whether these reactions were related to age, physical functioning, acceptance of illness, or self-efficacy. METHODS:Thirty-four patients with early RA (< 2 years since diagnosis) ...

journal_title：Scandinavian journal of rheumatology

authors： Treharne GJ,Lyons AC,Booth DA,Mason SR,Kitas GD

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:The objective was to prospectively evaluate the short as well as the long-term effects of intensive physiotherapy in a stable, sunny and warm climate on physical function and health related quality of life in patients with rheumatoid arthritis (RA) and spondylarthropathies (SpA). METHODS:Ninety-three Swedish...

journal_title：Scandinavian journal of rheumatology

authors： Hafström I,Hallengren M

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To compare bone mass (BMD) in women with fibromyalgia (FM) with healthy females, and to evaluate whether self-reported pain and lack of functional capacity correlate to reduced BMD in FM patients. METHODS:Thirty-one FM patients (20 pre- and 11 postmenopausal) and fourty-one healthy women (30 pre- and 10 post...

journal_title：Scandinavian journal of rheumatology

authors： Jensen B,Wittrup IH,Bliddal H,Danneskiold-Samsøe B,Faber J

更新日期：2003-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an uncommon immunological disorder with multisystemic involvement. Neurological and neuropsychiatric manifestations in this disease are multifactorial and can involve any part of this system. We describe one patient presenting with spastic quadriparesis as an early clinical manife...

journal_title：Scandinavian journal of rheumatology

authors： Gupta A,Singh S,Singh P,Ahluwalia J,Rath S,Minz RW

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To establish by ultrasonography (US) the frequency of calcaneal entheses involvement in erosive osteoarthritis (EOA), nodal osteoarthritis (NOA), RA and PsA, and to compare these results in order to aid clinicians in the differential diagnosis among these diseases. A comparison between US results and radiogra...

journal_title：Scandinavian journal of rheumatology

authors： Falsetti P,Frediani B,Fioravanti A,Acciai C,Baldi F,Filippou G,Marcolongo R

更新日期：2003-01-01 00:00:00